幽門螺桿菌感染在世界各地都有發生，但其流行程度在不同國家和同一國家內不同人群之間差別很大。幽門螺桿菌感染的總體流行程度與社會經濟條件密切相關。在許多發展中國家，中年人的患病率超過80%，而在工業化國家，這一比例為20%至50%。發展中國家的感染率高于發達國家。在發達國家，雖然兒童感染的總體流行率低于10%，但在社會經濟條件惡劣的兒童中，高達50%的兒童受到感染。在發展中國家，多達80%的10歲以下兒童受到感染。印度0-4歲、5-9歲和10-19歲年齡組的感染率分別為22%、56%和87%。重要的問題是，在整個發達國家，這種感染在兒童中很罕見，而在發展中國家，這種感染在兒童中很常見。可以看出，H的差異無統計學意義。男性和女性兒童之間的幽門螺桿菌感染。發展中國家的研究表明，直到上個世紀，幾乎所有的人類都攜帶H。幽門螺桿菌或胃里的相關細菌，但隨著社會經濟的發展，感染幽門螺桿菌的兒童越來越少。H。發達國家幽門螺桿菌感染率為0.3%-0.7%，發展中國家為6% - 14%。
Infection with H. pylori occurs worldwide, but the prevalence varies greatly among countries and among population groups within the same country. The overall prevalence of H. pylori infection is strongly correlated with socioeconomic conditions. The prevalence among middle-aged adults is over 80 percent in many developing countries, as compared with 20 to 50 percent in industrialized countries.Prevalence of infection is higher in developing countries than that of developed nations. In developed countries,although overall prevalance of infection in young children is <10%, up to 50 % of children living in poor socio economic conditions are infected. Upto 80 % of children under age of 10 years are infected in developing countries. Prevalance of infection in India is 22%,56% and 87% 0-4,5-9 and 10-19 years age group respectively. Important issue is that ,throughout the developed countries ,the infection is rare among children where as in developing nations it is common in children. It has been seen that there is no statistical difference of H.pylori infection between male and female children. Studies in developing countries suggest that,untill the last century ,nearly all humans carried H.pylori or closely related bacteria in their stomachs,but with socio economic development fewer children are acquiring H.pylori.Annual incidence of H.pylori infection is 0.3%-0.7% in developed countries and 6-14 % in developing nations.